Twisted Tower Wiki - System Requirements
Minimum
OSWindows 10 64-bit
ProcessorIntel Core i5-6600 / AMD Ryzen 5 2600
Memory8 GB
GraphicsNVIDIA GeForce GTX 670 / AMD Radeon RX 570 / Intel Arc B580
Storage8 GB
Recommended
OSWindows 11 64-bit
ProcessorIntel Core i5-8400 / AMD Ryzen 5 2600
Memory16 GB
GraphicsNVIDIA GeForce GTX 1660 / AMD Radeon Vega FE
Storage8 GB
Source: Official 3D Realms game page
Confirmed directly via the official 3D Realms game page. A 64-bit processor and operating system are required on both tiers.